Department of Chemical Engineering


Alexander A. Shestopalov

Assistant Professor
Duke University, PhD, 2009

248 Gavett Hall
(585) 276-5434


Selected Honors & Awards

Burroughs Wellcome (2007) and Hobbs Endowment (2009) Awards, Duke University


CHE 225: Thermodynamics

CHE 292/492: Biointerfaces

Recent Publications

Bowers, C. M.; Toone, E. J.; Clark, R. L.; Shestopalov, A. A. “Soft lithographic functionalization and patterning oxide-free silicon,” Journal of Visualized Experiments, accepted.

Shestopalov, A. A.; Morris, C. J.; Vogen, B. N.; Hoertz, A.; Clark, R. L.; Toone, E. J. “A soft-lithographic approach to functionalization and nanopatterning oxide-free silicon,” Langmuir 2011, 27, 6478 – 6485.

Morris, C. J.; Shestopalov, A. A.; Gold, B. H.; Clark, R. L.; Toone, Eric J. “Patterning NHS-terminated SAMs on Germanium,” Langmuir 2011, 27, 6486 – 6489.

Shestopalov, A. A.; Clark, R. L.; Toone, E. J. “Inkless Microcontact Printing on SAMs of Boc- and TBS-Protected Thiols,” Nano Letters 2010, 10, 43 – 46.

Shestopalov, A. A.; Clark, R. L.; Toone, E. J.; “Inkless Microcontact Printing on Self-Assembled Monolayers of Fmoc-Protected Aminothiols,” Journal of the American Chemical Society 2007, 129, 13818–13819.

Research Interests

Colloidal Self-Assembly; Nanopatterning Techniques ; Nanostructured Materials; Interfacial Phenomena; Organic Chemistry

Research Overview

Our research focuses on the development of new unconventional fabrication and patterning techniques and the use of these techniques in preparation of functional micro- and nanostructured devices. Inorganic multicomponent colloids: The non-symmetric structure of Janus particles produces novel physical properties and unusual aggregation behavior that makes these materials attractive candidates for drug delivery and as nano-sensors and nano-probes, microscopic mixers, and emulsifiers. In our research we focus on the development of new preparation pathways for the inorganic metal-oxide Janus particles and on the development of procedures for their orthogonal functionalization. We also develop methods for their targeted immobilization and aggregation and investigate some of the applications of these particles as potential photonic crystals, plasmonic sensors, SERS and PEF imaging agents, small molecules carriers, and switchable devices. Organic photovoltaic devices: One of the most important characteristics of the organic solar cells is the efficiency of a heterojunction between electron- and hole-transporting layers. Our research is focused on the development of simple nanoimprinting techniques capable of nanostructuring organic semiconductors to create an ordered p-n heterojunction. We are also working on the development of novel large-area patterning methods for interconnecting organic semiconductors using solution-based processing techniques.